Collapse Section. Hailey-Hailey disease, also known as. › Genetics › Genetic Conditions. Hailey-Hailey disease is a rare genetic disorder that is characterized by blisters and erosions most often affecting the neck, armpits, skin folds and. Benign familial pemphigus is also known as Hailey–Hailey disease. It is a rare hereditary blistering skin disease first described by the Hailey brothers in. A small error in the DNA code of a gene on chromosome number 3 (one of the 46 chromosomes that we all have) has been shown to cause Hailey-Hailey disease. Hailey–Hailey disease, or familial benign chronic pemphigus: or familial benign pemphigus: was originally described by the Hailey brothers in. A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Hailey-Hailey disease. Hailey-Hailey disease is a genetic skin disease that causes blistering. Signs and symptoms include a painful rash and blistering in skin folds, such as the. m Followers, 2 Following, 0 Posts - See Instagram photos and videos from hayley (@yelyahwilliams). k Followers, Following, Posts - See Instagram photos and videos from Hayley Hughes (@).